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| - | [[Image:2g8m.gif|left|200px]] | + | #REDIRECT [[4gev]] This PDB entry is obsolete and replaced by 4gev |
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| - | {{Structure
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| - | |PDB= 2g8m |SIZE=350|CAPTION= <scene name='initialview01'>2g8m</scene>, resolution 1.30Å
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| - | |SITE=
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| - | |LIGAND= <scene name='pdbligand=CB3:10-PROPARGYL-5,8-DIDEAZAFOLIC+ACID'>CB3</scene>, <scene name='pdbligand=CXM:N-CARBOXYMETHIONINE'>CXM</scene>, <scene name='pdbligand=UMP:2'-DEOXYURIDINE+5'-MONOPHOSPHATE'>UMP</scene>
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| - | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span>
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| - | |GENE= thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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| - | |DOMAIN=
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| - | |RELATEDENTRY=[[2g86|2G86]], [[2g89|2G89]], [[2g8a|2G8A]], [[2g8d|2G8D]]
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| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g8m OCA], [http://www.ebi.ac.uk/pdbsum/2g8m PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2g8m RCSB]</span>
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| - | }}
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| - | '''Escherichia coli thymidylate synthase Y209W in complex with substrate, dUMP, and a cofactor analog, CB3717'''
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| - | ==About this Structure==
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| - | 2G8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G8M OCA].
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| - | [[Category: Escherichia coli]]
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| - | [[Category: Single protein]]
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| - | [[Category: Thymidylate synthase]]
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| - | [[Category: Lee, T T.]]
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| - | [[Category: Newby, Z.]]
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| - | [[Category: Stroud, R M.]]
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| - | [[Category: alpha/beta protein]]
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| - | [[Category: antifolate]]
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| - | [[Category: beta sheet]]
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| - | [[Category: dump]]
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| - | [[Category: dump binding site mutant]]
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| - | [[Category: ternary complex]]
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:13:18 2008''
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