User:Evie Nguyen/Sandbox 1

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= HRP1 =
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=HRP1=
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HRP1 is found in ''Saccharomyces cerevisiae'', commonly known as "baker's yeast." It was discovered via solution NMR and then released to the RCSB Protein Data Bank with the ID "2CJK" in 2006. HRP1 is the RNA recognition domain of the Cleavage Factor Complex, positioning the RNA cleavage site prior to polyadenylation. It is composed of 2 RNA binding domains that recognize a specific 5'-AUAUAU-3' sequence of RNA.
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[[Image:2CJK.png|100 px|left|thumb|Figure Legend]]<Structure load='2CJK' size='350' frame='true' align='right' caption='2CJK' scene='Insert optional scene name here' />
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== Function ==
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This is a default text for your page '''Evie Nguyen/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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<scene name='78/782620/2cjk_residues_100-200-2/1'>2CJK Residues 100-200</scene>
 
== RNA Binding ==
== RNA Binding ==
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<StructureSection load='2cjk' size='400' side='right' caption='(PDB entry [[2cjk]])' scene=''>
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The ribonucleotides of the recognized sequence 5'-AUAUAU-3' are designated from 5'-3' Ade2, Ade4, and Ade6; and Ura3, Ura5, and Ura7. The first two bases, Ade2 and Ura3, bind to the second RNA binding domain, and the remaining bases of the sequence bind to the first RNA binding domain. Each ribonucleotide has distinguishing interactions with the protein including
The ribonucleotides of the recognized sequence 5'-AUAUAU-3' are designated from 5'-3' Ade2, Ade4, and Ade6; and Ura3, Ura5, and Ura7. The first two bases, Ade2 and Ura3, bind to the second RNA binding domain, and the remaining bases of the sequence bind to the first RNA binding domain. Each ribonucleotide has distinguishing interactions with the protein including
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<scene name='78/782620/2cjk_residues_100-200-2/1'>2CJK Residues 100-200</scene>
=== Adenines ===
=== Adenines ===
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== Disease ==
== Disease ==
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== Relevance ==
== Relevance ==
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[[Image:Ade2-Ura3_H-Bonding.png|100px|left|thumb|Figure Legend]]
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[[Image:Ade2-Ura3_H-Bonding.png|100px|left|thumb|Hydrogen bond between Ade2 and Ura3]]

Current revision

Contents

HRP1

Function

RNA Binding

(PDB entry 2cjk)

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References


Hydrogen bond between Ade2 and Ura3
Hydrogen bond between Ade2 and Ura3

Proteopedia Page Contributors and Editors (what is this?)

Evie Nguyen

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