1vka

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==Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment==
==Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment==
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<StructureSection load='1vka' size='340' side='right' caption='[[1vka]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='1vka' size='340' side='right'caption='[[1vka]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vka]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VKA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vka]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VKA FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPRE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vka OCA], [http://pdbe.org/1vka PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vka RCSB], [http://www.ebi.ac.uk/pdbsum/1vka PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vka ProSAT], [http://www.topsan.org/Proteins/SECSG/1vka TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vka OCA], [https://pdbe.org/1vka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vka RCSB], [https://www.ebi.ac.uk/pdbsum/1vka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vka ProSAT], [https://www.topsan.org/Proteins/SECSG/1vka TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN]] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
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[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[End-binding protein|End-binding protein]]
*[[End-binding protein|End-binding protein]]
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*[[Microtubule-associated protein|Microtubule-associated protein]]
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*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Dailey, H A]]
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[[Category: Large Structures]]
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[[Category: Dailey, T A]]
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[[Category: Dailey HA]]
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[[Category: Liu, Z J]]
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[[Category: Dailey TA]]
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[[Category: Mayer, M R]]
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[[Category: Liu Z-J]]
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[[Category: Rose, J P]]
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[[Category: Mayer MR]]
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[[Category: Structural genomic]]
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[[Category: Rose JP]]
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[[Category: Schubot, F D]]
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[[Category: Schubot FD]]
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[[Category: Shah, A]]
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[[Category: Shah A]]
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[[Category: Tempel, W]]
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[[Category: Tempel W]]
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[[Category: Wang, B C]]
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[[Category: Wang B-C]]
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[[Category: Homo sapien]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Q15691]]
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[[Category: Secsg]]
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[[Category: Unknown function]]
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Current revision

Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment

PDB ID 1vka

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