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1w8m

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==Enzymatic and Structural Characterisation of Non Peptide Ligand Cyclophilin Complexes==
==Enzymatic and Structural Characterisation of Non Peptide Ligand Cyclophilin Complexes==
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<StructureSection load='1w8m' size='340' side='right' caption='[[1w8m]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='1w8m' size='340' side='right'caption='[[1w8m]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w8m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W8M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w8m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W8M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E1P:ETHYL+OXO(PIPERIDIN-1-YL)ACETATE'>E1P</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w7y|1w7y]], [[1w8l|1w8l]], [[1w8v|1w8v]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E1P:ETHYL+OXO(PIPERIDIN-1-YL)ACETATE'>E1P</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w8m OCA], [https://pdbe.org/1w8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w8m RCSB], [https://www.ebi.ac.uk/pdbsum/1w8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w8m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w8m OCA], [http://pdbe.org/1w8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w8m RCSB], [http://www.ebi.ac.uk/pdbsum/1w8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w8m ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Cyclophilin|Cyclophilin]]
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Large Structures]]
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[[Category: Kontopidis, G]]
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[[Category: Kontopidis G]]
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[[Category: Taylor, P]]
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[[Category: Taylor P]]
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[[Category: Walkinshaw, M]]
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[[Category: Walkinshaw M]]
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[[Category: Isomerase]]
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[[Category: Multigene family]]
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[[Category: Non peptide ligand]]
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[[Category: Rotamase]]
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Current revision

Enzymatic and Structural Characterisation of Non Peptide Ligand Cyclophilin Complexes

PDB ID 1w8m

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