This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1wju
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1== | ==Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1== | ||
| - | <StructureSection load='1wju' size='340' side='right' caption='[[1wju | + | <StructureSection load='1wju' size='340' side='right'caption='[[1wju]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wju]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1wju]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WJU FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wju OCA], [https://pdbe.org/1wju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wju RCSB], [https://www.ebi.ac.uk/pdbsum/1wju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wju ProSAT], [https://www.topsan.org/Proteins/RSGI/1wju TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NUB1_HUMAN NUB1_HUMAN] Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.<ref>PMID:16707496</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Inoue M]] |
| - | [[Category: | + | [[Category: Kigawa T]] |
| - | [[Category: | + | [[Category: Koshiba S]] |
| - | [[Category: Tochio | + | [[Category: Tochio N]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
| - | [[Category: Yoneyama | + | [[Category: Yoneyama M]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1
| |||||||||||
Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Koshiba S | Tochio N | Yokoyama S | Yoneyama M
