This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1x4n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:58, 9 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Solution structure of KH domain in FUSE binding protein 1==
==Solution structure of KH domain in FUSE binding protein 1==
-
<StructureSection load='1x4n' size='340' side='right' caption='[[1x4n]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='1x4n' size='340' side='right'caption='[[1x4n]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1x4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X4N FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1x4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X4N FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Fubp1, D3Ertd330e ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4n OCA], [http://pdbe.org/1x4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x4n RCSB], [http://www.ebi.ac.uk/pdbsum/1x4n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4n ProSAT], [http://www.topsan.org/Proteins/RSGI/1x4n TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4n OCA], [https://pdbe.org/1x4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4n RCSB], [https://www.ebi.ac.uk/pdbsum/1x4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4n ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4n TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/FUBP1_MOUSE FUBP1_MOUSE]] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription (By similarity).
+
[https://www.uniprot.org/uniprot/FUBP1_MOUSE FUBP1_MOUSE] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 21: Line 21:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Large Structures]]
-
[[Category: He, F]]
+
[[Category: Mus musculus]]
-
[[Category: Inoue, M]]
+
[[Category: He F]]
-
[[Category: Kigawa, T]]
+
[[Category: Inoue M]]
-
[[Category: Muto, Y]]
+
[[Category: Kigawa T]]
-
[[Category: Structural genomic]]
+
[[Category: Muto Y]]
-
[[Category: Shirouzu, M]]
+
[[Category: Shirouzu M]]
-
[[Category: Terada, T]]
+
[[Category: Terada T]]
-
[[Category: Yokoyama, S]]
+
[[Category: Yokoyama S]]
-
[[Category: Kh domain]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rna binding protein]]
+
-
[[Category: Rsgi]]
+

Current revision

Solution structure of KH domain in FUSE binding protein 1

PDB ID 1x4n

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools