1woy

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==Crystal structure of methionyl tRNA synthetase Y225F mutant from Thermus thermophilus==
==Crystal structure of methionyl tRNA synthetase Y225F mutant from Thermus thermophilus==
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<StructureSection load='1woy' size='340' side='right' caption='[[1woy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1woy' size='340' side='right'caption='[[1woy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1woy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WOY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1woy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WOY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1woy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1woy OCA], [http://pdbe.org/1woy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1woy RCSB], [http://www.ebi.ac.uk/pdbsum/1woy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1woy ProSAT], [http://www.topsan.org/Proteins/RSGI/1woy TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1woy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1woy OCA], [https://pdbe.org/1woy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1woy RCSB], [https://www.ebi.ac.uk/pdbsum/1woy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1woy ProSAT], [https://www.topsan.org/Proteins/RSGI/1woy TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
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[https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Methionine--tRNA ligase]]
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[[Category: Thermus thermophilus]]
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[[Category: Konno, M]]
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[[Category: Konno M]]
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[[Category: Nureki, O]]
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[[Category: Nureki O]]
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[[Category: Structural genomic]]
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[[Category: Takeda R]]
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[[Category: Takeda, R]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Class 1a aminoacyl-trna synthetase]]
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[[Category: Ligase]]
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[[Category: Metal-binding]]
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[[Category: Mutation at tyr225]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rossmann fold]]
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[[Category: Rsgi]]
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Current revision

Crystal structure of methionyl tRNA synthetase Y225F mutant from Thermus thermophilus

PDB ID 1woy

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