Cytochrome b5
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<StructureSection load='1b5m' size='350' side='right' caption='Rat heme-containing cytochrome b5 (PDB entry [[1b5m]])' scene='49/490878/Cv/1'> | <StructureSection load='1b5m' size='350' side='right' caption='Rat heme-containing cytochrome b5 (PDB entry [[1b5m]])' scene='49/490878/Cv/1'> | ||
- | '''Cytochrome b5''' (CB) functions as an electron transport carrier for several membrane-bound oxygenases. <scene name='49/490878/Cv/2'>CB is heme-containing protein</scene>. The microsomal and mitochondrial CB are membrane-bound while bacterial and other animal tissue CB are soluble. | + | '''Cytochrome b5''' (CB) functions as an electron transport carrier for several membrane-bound oxygenases<ref>PMID:12481306</ref>. <scene name='49/490878/Cv/2'>CB is heme-containing protein</scene>. The microsomal and mitochondrial CB are membrane-bound while bacterial and other animal tissue CB are soluble. |
- | + | *'''Cytochrome b558''' is a flavoprotein which is a component of NADPH oxidase<ref>PMID:1324665</ref> | |
- | + | *'''Cytochrome b562''' is the the b-type cytochrome from ''E. coli''.<ref>PMID:12559387</ref> | |
- | + | See also [[Hemeproteins]]. | |
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- | + | ==3D structures of cytochrome b5== | |
+ | [[Cytochrome b5 3D structures]] | ||
- | + | </StructureSection> | |
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- | **[[256b]] – EcCB + heme – ''Escherichia coli''<br /> | ||
- | **[[1qpu]] - EcCB + heme – NMR<BR /> | ||
- | **[[1qq3]] - EcCB (mutant) + heme – NMR<BR /> | ||
- | **[[1lm3]], [[2bc5]], [[2qla]], [[3c62]], [[3c63]], [[3de8]], [[3de9]], [[3foo]], [[3fop]], [[3hni]], [[3hnj]], [[3hnk]], [[3hnl]], [[3l1m]], [[3iq5]], [[3iq6]], [[3m79]], [[3nmi]], [[3nmj]], [[3nmk]], [[3m15]], [[3m4b]], [[3m4c]] - EcCB (mutant) + heme<br /> | ||
- | **[[1apc]] – EcCB – NMR<BR /> | ||
- | **[[1m6t]] - EcCB (mutant) | ||
- | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
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References
- ↑ Porter TD. The roles of cytochrome b5 in cytochrome P450 reactions. J Biochem Mol Toxicol. 2002;16(6):311-6. PMID:12481306 doi:10.1002/jbt.10052
- ↑ Sumimoto H, Sakamoto N, Nozaki M, Sakaki Y, Takeshige K, Minakami S. Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein. Biochem Biophys Res Commun. 1992 Aug 14;186(3):1368-75. PMID:1324665 doi:10.1016/s0006-291x(05)81557-8
- ↑ Schenkman JB, Jansson I. The many roles of cytochrome b5. Pharmacol Ther. 2003 Feb;97(2):139-52. PMID:12559387