6cv9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cytoplasmic domain of mTRPC6== | |
| - | + | <SX load='6cv9' size='340' side='right' viewer='molstar' caption='[[6cv9]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cv9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CV9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cv9 OCA], [https://pdbe.org/6cv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cv9 RCSB], [https://www.ebi.ac.uk/pdbsum/6cv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cv9 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRPC6_MOUSE TRPC6_MOUSE] Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.[UniProtKB:Q9Y210] | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Azumaya CM]] | ||
| + | [[Category: Cordero-Morales JF]] | ||
| + | [[Category: Nakagawa T]] | ||
| + | [[Category: Sierra-Valdez FJ]] | ||
Current revision
Cytoplasmic domain of mTRPC6
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