This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4x6t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:41, 27 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==M.tuberculosis betalactamase complexed with inhibitor EC19==
==M.tuberculosis betalactamase complexed with inhibitor EC19==
-
<StructureSection load='4x6t' size='340' side='right' caption='[[4x6t]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='4x6t' size='340' side='right'caption='[[4x6t]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4x6t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X6T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X6T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4x6t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X6T FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3Y6:3-[(2R)-2-(DIHYDROXYBORANYL)-2-{[(2R)-2-{[(4-ETHYL-2,3-DIOXO-3,4-DIHYDROPYRAZIN-1(2H)-YL)CARBONYL]AMINO}-2-(4-HYDROXYPHENYL)ACETYL]AMINO}ETHYL]BENZOIC+ACID'>3Y6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaC, blaA, Rv2068c, MTCY49.07c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3Y6:3-[(2R)-2-(DIHYDROXYBORANYL)-2-{[(2R)-2-{[(4-ETHYL-2,3-DIOXO-3,4-DIHYDROPYRAZIN-1(2H)-YL)CARBONYL]AMINO}-2-(4-HYDROXYPHENYL)ACETYL]AMINO}ETHYL]BENZOIC+ACID'>3Y6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x6t OCA], [https://pdbe.org/4x6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x6t RCSB], [https://www.ebi.ac.uk/pdbsum/4x6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x6t ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x6t OCA], [http://pdbe.org/4x6t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x6t RCSB], [http://www.ebi.ac.uk/pdbsum/4x6t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x6t ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 21:
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
+
[[Category: Large Structures]]
-
[[Category: Myctu]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Hazra, S]]
+
[[Category: Hazra S]]
-
[[Category: Beta-lactam]]
+
-
[[Category: Boronate]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Penicillin binding protein]]
+
-
[[Category: Structure based drug development]]
+
-
[[Category: Transition state inhibitor]]
+

Current revision

M.tuberculosis betalactamase complexed with inhibitor EC19

PDB ID 4x6t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4x6t"
Personal tools