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1x68

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==Solution structures of the C-terminal LIM domain of human FHL5 protein==
==Solution structures of the C-terminal LIM domain of human FHL5 protein==
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<StructureSection load='1x68' size='340' side='right' caption='[[1x68]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1x68' size='340' side='right'caption='[[1x68]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1x68]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X68 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1x68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X68 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FHL5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x68 OCA], [http://pdbe.org/1x68 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x68 RCSB], [http://www.ebi.ac.uk/pdbsum/1x68 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x68 ProSAT], [http://www.topsan.org/Proteins/RSGI/1x68 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x68 OCA], [https://pdbe.org/1x68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x68 RCSB], [https://www.ebi.ac.uk/pdbsum/1x68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x68 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x68 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FHL5_HUMAN FHL5_HUMAN]] May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.<ref>PMID:11327716</ref>
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[https://www.uniprot.org/uniprot/FHL5_HUMAN FHL5_HUMAN] May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.<ref>PMID:11327716</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x68 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x68 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[Zinc Fingers|Zinc Fingers]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Inoue, M]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Koshiba, S]]
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[[Category: Kigawa T]]
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[[Category: Nameki, N]]
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[[Category: Koshiba S]]
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[[Category: Structural genomic]]
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[[Category: Nameki N]]
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[[Category: Sasagawa, A]]
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[[Category: Sasagawa A]]
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[[Category: Sato, M]]
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[[Category: Sato M]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: An actin-interacting protein]]
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[[Category: Four-and-a-half lim protein 5]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Protein binding]]
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[[Category: Rsgi]]
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[[Category: Zinc finger domain]]
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Current revision

Solution structures of the C-terminal LIM domain of human FHL5 protein

PDB ID 1x68

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