2h6y

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[[Image:2h6y.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group==
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|PDB= 2h6y |SIZE=350|CAPTION= <scene name='initialview01'>2h6y</scene>, resolution 2.400&Aring;
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<StructureSection load='2h6y' size='340' side='right'caption='[[2h6y]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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<table><tr><td colspan='2'>[[2h6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H6Y FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Lyase Lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.7.1.4. 4.7.1.4.] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE= trxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6y OCA], [https://pdbe.org/2h6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h6y RCSB], [https://www.ebi.ac.uk/pdbsum/2h6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h6y ProSAT]</span></td></tr>
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|RELATEDENTRY=[[2trx|2TRX]], [[1zzy|1ZZY]], [[2fch|2FCH]], [[2fd3|2FD3]], [[2h6x|2H6X]], [[2h6z|2H6Z]], [[2h70|2H70]], [[2h71|2H71]], [[2h72|2H72]], [[2h73|2H73]], [[2h74|2H74]], [[2h75|2H75]], [[2h76|2H76]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6y OCA], [http://www.ebi.ac.uk/pdbsum/2h6y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h6y RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/2h6y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h6y ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group'''
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==See Also==
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*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2H6Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6Y OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lyase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Gavira JA]]
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[[Category: Gavira, J A.]]
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[[Category: Godoy-Ruiz R]]
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[[Category: Godoy-Ruiz, R.]]
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[[Category: Ibarra-Molero B]]
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[[Category: Ibarra-Molero, B.]]
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[[Category: Sanchez-Ruiz JM]]
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[[Category: Sanchez-Ruiz, J M.]]
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[[Category: alpha beta]]
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[[Category: electron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:26:22 2008''
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Current revision

Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group

PDB ID 2h6y

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