1xyz

<StructureSection load='1xyz' size='340' side='right' caption='[[1xyz]], [[Resolution|resolution]] 1.40&Aring;' scene=''>

<table><tr><td colspan='2'>[[1xyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_yutin_and_galperin_2013 "ruminiclostridium thermocellum" yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XYZ FirstGlance]. <br>

</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xyz OCA], [http://pdbe.org/1xyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xyz RCSB], [http://www.ebi.ac.uk/pdbsum/1xyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xyz ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

The structure of Clostridium thermocellum endoglucanase CelC, a member of the largest cellulase family (family A), has been determined at 2.15 A resolution. The protein folds into an (alpha/beta)8 barrel, with a deep active-site cleft generated by the insertion of a helical subdomain. The structure of the catalytic core of xylanase XynZ, which belongs to xylanase family F, has been determined at 1.4 A resolution. In spite of significant differences in substrate specificity and structure (including the absence of the helical subdomain), the general polypeptide folding pattern, architecture of the active site and catalytic mechanism of XynZ and CelC are similar, suggesting a common evolutionary origin.

A common protein fold and similar active site in two distinct families of beta-glycanases.,Dominguez R, Souchon H, Spinelli S, Dauter Z, Wilson KS, Chauvaux S, Beguin P, Alzari PM Nat Struct Biol. 1995 Jul;2(7):569-76. PMID:7664125<ref>PMID:7664125</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 1xyz" style="background-color:#fffaf0;"></div>

==See Also==

*[[User:Eric Martz/Entertaining PDB codes|User:Eric Martz/Entertaining PDB codes]]

== References ==

<references/>

[[Category: Ruminiclostridium thermocellum yutin and galperin 2013]]

[[Category: Endo-1,4-beta-xylanase]]

[[Category: Alzari, P M]]

[[Category: Dominguez, R]]

[[Category: Spinelli, S]]

[[Category: Xylanase]]