6cpi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of SH3 domain from Shank1== | |
| + | <StructureSection load='6cpi' size='340' side='right'caption='[[6cpi]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6cpi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CPI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CPI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cpi OCA], [https://pdbe.org/6cpi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cpi RCSB], [https://www.ebi.ac.uk/pdbsum/6cpi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cpi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SHAN1_HUMAN SHAN1_HUMAN] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. | ||
| - | + | ==See Also== | |
| - | + | *[[Shank protein|Shank protein]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ishida H]] | ||
| + | [[Category: Vogel HJ]] | ||
Current revision
Solution structure of SH3 domain from Shank1
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