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6czb

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'''Unreleased structure'''
 
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The entry 6czb is ON HOLD until Paper Publication
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==Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) - promiscuous binding mode with disordered nucleoside==
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<StructureSection load='6czb' size='340' side='right'caption='[[6czb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6czb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CZB FirstGlance]. <br>
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Description: Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) -promiscuous binding mode with disordered nucleoside
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
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[[Category: Polyak, S.W]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6czb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6czb OCA], [https://pdbe.org/6czb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6czb RCSB], [https://www.ebi.ac.uk/pdbsum/6czb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6czb ProSAT]</span></td></tr>
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[[Category: Bruning, J.B]]
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</table>
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[[Category: Thompson, A.P]]
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== Function ==
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[[Category: Wegener, K.L]]
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[https://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bruning JB]]
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[[Category: Polyak SW]]
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[[Category: Thompson AP]]
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[[Category: Wegener KL]]

Current revision

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) - promiscuous binding mode with disordered nucleoside

PDB ID 6czb

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