This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4cyi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:38, 14 September 2022) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
{{Large structure}}
+
 
==Chaetomium thermophilum Pan3==
==Chaetomium thermophilum Pan3==
-
<StructureSection load='4cyi' size='340' side='right' caption='[[4cyi]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
+
<StructureSection load='4cyi' size='340' side='right'caption='[[4cyi]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4cyi]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_144.50 Cbs 144.50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CYI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4cyi]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CYI FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cyi OCA], [https://pdbe.org/4cyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cyi RCSB], [https://www.ebi.ac.uk/pdbsum/4cyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cyi ProSAT]</span></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cyj|4cyj]]</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cyi OCA], [http://pdbe.org/4cyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cyi RCSB], [http://www.ebi.ac.uk/pdbsum/4cyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cyi ProSAT]</span></td></tr>
+
</table>
</table>
-
{{Large structure}}
+
== Function ==
 +
[[https://www.uniprot.org/uniprot/PAN3_CHATD PAN3_CHATD]] Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.[HAMAP-Rule:MF_03181]<ref>PMID:24872509</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cbs 144 50]]
+
[[Category: Chaetomium thermophilum]]
-
[[Category: Allen, M D]]
+
[[Category: Large Structures]]
-
[[Category: Bycroft, M]]
+
[[Category: Allen MD]]
-
[[Category: Gordiyenko, Y]]
+
[[Category: Bycroft M]]
-
[[Category: McLaughlin, S H]]
+
[[Category: Gordiyenko Y]]
-
[[Category: Meineke, B]]
+
[[Category: McLaughlin SH]]
-
[[Category: Olsen, T M]]
+
[[Category: Meineke B]]
-
[[Category: Passmore, L A]]
+
[[Category: Olsen TM]]
-
[[Category: Robinson, C V]]
+
[[Category: Passmore LA]]
-
[[Category: Stewart, M]]
+
[[Category: Robinson CV]]
-
[[Category: Valkov, E]]
+
[[Category: Stewart M]]
-
[[Category: Wolf, J]]
+
[[Category: Valkov E]]
-
[[Category: Transferase]]
+
[[Category: Wolf J]]

Current revision

Chaetomium thermophilum Pan3

PDB ID 4cyi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cyi"
Personal tools