1yta

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==Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli==
==Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli==
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<StructureSection load='1yta' size='340' side='right' caption='[[1yta]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1yta' size='340' side='right'caption='[[1yta]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1yta]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YTA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1yta]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YTA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yta OCA], [https://pdbe.org/1yta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yta RCSB], [https://www.ebi.ac.uk/pdbsum/1yta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yta ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yta OCA], [http://pdbe.org/1yta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yta RCSB], [http://www.ebi.ac.uk/pdbsum/1yta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yta ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ORN_ECOLI ORN_ECOLI]] 3'-to-5' exoribonuclease specific for small oligoribonucleotides 2 to 5 nucleotides in length, as well as small (2 to 5 nucleotides) ssDNA oligomers. Probably responsible for the final step in mRNA degradation.<ref>PMID:9573169</ref> <ref>PMID:7608090</ref> <ref>PMID:16682444</ref>
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[https://www.uniprot.org/uniprot/ORN_ECOLI ORN_ECOLI] 3'-to-5' exoribonuclease specific for small oligoribonucleotides 2 to 5 nucleotides in length, as well as small (2 to 5 nucleotides) ssDNA oligomers. Probably responsible for the final step in mRNA degradation.<ref>PMID:9573169</ref> <ref>PMID:7608090</ref> <ref>PMID:16682444</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/1yta_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/1yta_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
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*[[Temp|Temp]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Fiedler, T J]]
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[[Category: Large Structures]]
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[[Category: Malhotra, A]]
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[[Category: Fiedler TJ]]
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[[Category: Zuo, Y]]
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[[Category: Malhotra A]]
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[[Category: Exonuclease]]
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[[Category: Zuo Y]]
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[[Category: Exoribonuclease]]
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[[Category: Hydrolase]]
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[[Category: Mrna decay]]
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[[Category: Nuclease]]
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[[Category: Ribonuclease]]
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[[Category: Rnase]]
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[[Category: Translation]]
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Current revision

Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli

PDB ID 1yta

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