5o9o

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==Crystal structure of ScGas2 in complex with compound 7.==
==Crystal structure of ScGas2 in complex with compound 7.==
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<StructureSection load='5o9o' size='340' side='right' caption='[[5o9o]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='5o9o' size='340' side='right'caption='[[5o9o]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5o9o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O9O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5o9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O9O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9PB:(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-(naphthalen-2-ylmethoxymethyl)-1,2,3-triazol-1-yl]-3,5-bis(oxidanyl)oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol'>9PB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9o OCA], [http://pdbe.org/5o9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o9o RCSB], [http://www.ebi.ac.uk/pdbsum/5o9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9o ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9PB:(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-(naphthalen-2-ylmethoxymethyl)-1,2,3-triazol-1-yl]-3,5-bis(oxidanyl)oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol'>9PB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9o OCA], [https://pdbe.org/5o9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o9o RCSB], [https://www.ebi.ac.uk/pdbsum/5o9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST]] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>
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[https://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aalten, D van]]
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[[Category: Large Structures]]
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[[Category: Castro-Lopez, J]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Delso, I]]
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[[Category: Castro-Lopez J]]
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[[Category: Fang, W]]
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[[Category: Delso I]]
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[[Category: Gomollon-Bel, F]]
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[[Category: Fang W]]
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[[Category: Hurtado-Guerrero, R]]
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[[Category: Gomollon-Bel F]]
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[[Category: Merino, P]]
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[[Category: Hurtado-Guerrero R]]
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[[Category: Navratilova, I]]
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[[Category: Merino P]]
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[[Category: Tejero, T]]
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[[Category: Navratilova I]]
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[[Category: Valero-Gonzalez, J]]
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[[Category: Tejero T]]
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[[Category: Afgel4]]
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[[Category: Valero-Gonzalez J]]
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[[Category: Aspergillus fumigatus]]
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[[Category: Van Aalten D]]
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[[Category: Cell wall remodeling]]
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[[Category: Fungal cell wall]]
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[[Category: Glucanosyltransferase]]
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[[Category: Scgas2]]
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[[Category: Transferase]]
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[[Category: Transglycosylase]]
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Current revision

Crystal structure of ScGas2 in complex with compound 7.

PDB ID 5o9o

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