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5xey
From Proteopedia
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==Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus== | ==Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus== | ||
| - | <StructureSection load='5xey' size='340' side='right' caption='[[5xey]], [[Resolution|resolution]] 1.82Å' scene=''> | + | <StructureSection load='5xey' size='340' side='right'caption='[[5xey]], [[Resolution|resolution]] 1.82Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5xey]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEY OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5xey]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacteroides_abscessus_ATCC_19977 Mycobacteroides abscessus ATCC 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XEY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=83X:1-[2,4,6-tris(oxidanyl)phenyl]ethanone'>83X</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xey OCA], [https://pdbe.org/5xey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xey RCSB], [https://www.ebi.ac.uk/pdbsum/5xey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xey ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHY_MYCA9 PHY_MYCA9] Catalyzes the hydrolytic C-C cleavage of phloretin to phloroglucinol and 3-(4-hydroxyphenyl)propionic acid. Can also hydrolyze monoacetylphloroglucinol (MAPG) but not 2,4-diacetylphloroglucinol (DAPG).<ref>PMID:30784195</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mycobacteroides abscessus ATCC 19977]] |
| - | [[Category: | + | [[Category: Han JT]] |
| - | [[Category: | + | [[Category: He YX]] |
| - | [[Category: | + | [[Category: Jia WJ]] |
| - | [[Category: | + | [[Category: Zhang Z]] |
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Current revision
Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
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