1zbl

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==Bacillus halodurans RNase H catalytic domain mutant D192N in complex with 12-mer RNA/DNA hybrid==
==Bacillus halodurans RNase H catalytic domain mutant D192N in complex with 12-mer RNA/DNA hybrid==
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<StructureSection load='1zbl' size='340' side='right' caption='[[1zbl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1zbl' size='340' side='right'caption='[[1zbl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zbl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZBL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zbl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZBL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zbf|1zbf]], [[1zbi|1zbi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zbl OCA], [https://pdbe.org/1zbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zbl RCSB], [https://www.ebi.ac.uk/pdbsum/1zbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zbl ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zbl OCA], [http://pdbe.org/1zbl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zbl RCSB], [http://www.ebi.ac.uk/pdbsum/1zbl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zbl ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1zbl" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zbl" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bachd]]
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[[Category: Alkalihalobacillus halodurans C-125]]
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[[Category: Ribonuclease H]]
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[[Category: Large Structures]]
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[[Category: Crouch, R J]]
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[[Category: Crouch RJ]]
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[[Category: Gaidamakov, S A]]
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[[Category: Gaidamakov SA]]
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[[Category: Nowotny, M]]
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[[Category: Nowotny M]]
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[[Category: Yang, W]]
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[[Category: Yang W]]
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[[Category: Dde motif]]
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[[Category: Hydrolase-rna-dna complex]]
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[[Category: Rna/dna hybrid]]
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[[Category: Rnase h]]
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Current revision

Bacillus halodurans RNase H catalytic domain mutant D192N in complex with 12-mer RNA/DNA hybrid

PDB ID 1zbl

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