This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Aminomutase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:16, 12 March 2019) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 33: Line 33:
TAM active site residues facilitate the deprotonation/reprotonation reaction. <scene name='71/715468/Cv/3'>The active site</scene> includes residues from both monomers in Tyrosine aminomutase (PDB code [[2ohy]]).<ref name="Ad">PMID:17516659</ref>
TAM active site residues facilitate the deprotonation/reprotonation reaction. <scene name='71/715468/Cv/3'>The active site</scene> includes residues from both monomers in Tyrosine aminomutase (PDB code [[2ohy]]).<ref name="Ad">PMID:17516659</ref>
- 
-
</StructureSection>
 
==3D structures of aminomutase==
==3D structures of aminomutase==
 +
[[Aminomutase 3D structures]]
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
</StructureSection>
-
{{#tree:id=OrganizedByTopic|openlevels=0|
+
-
 
+
-
*Phenylalanine aminomutase
+
-
 
+
-
**[[4c5u]], [[4c6g]] – TwPAM (mutant) – ''Taxus wallichiana''<br />
+
-
**[[1y2m]], [[1t6p]] – RtPAM – ''Rhodosporidium toruloides''<br />
+
-
 
+
-
*Phenylalanine aminomutase complexes
+
-
 
+
-
**[[4v2q]], [[4v2r]], [[4bab]], [[2yii]] – TwPAM + peptide derived chromophore <br />
+
-
**[[4baa]] – TwPAM (mutant) + peptide derived chromophore <br />
+
-
**[[4c5r]] – TwPAM + peptide derived chromophore + phenylpropanoate derivative<br />
+
-
**[[4c5s]] – TwPAM (mutant) + peptide derived chromophore + phenylpropanoate derivative<br />
+
-
**[[4cq5]] – TwPAM (mutant) + peptide derived chromophore + phenylethylenecarboxylate<br />
+
-
**[[3nz4]] – PAM + peptide derived chromophore + phenylethylenecarboxylate – Taxus canadensis<br />
+
-
**[[3unv]] – PAM + peptide derived chromophore + phenylpropanoate derivative + phenylalanine – ''Pantoea agglomerans'' <br />
+
-
**[[3czo]], [[2nyn]] – PAM + peptide derived chromophore – ''Anabaena variabilis''<br />
+
-
**[[2nyf]] – PAM + peptide derived chromophore – ''Nostoc punctiforme''<br />
+
-
**[[1w27]] – PAM + peptide derived chromophore – ''Petroselinum crispum''<br />
+
-
**[[1t6j]] – RtPAM + carboxycinnamic acid<br />
+
-
 
+
-
*Tyrosine-2,3-aminomutase complexes
+
-
 
+
-
**[[2ohy]] – SgTAM + peptide derived chromophore – ''Streptomyces globisporus''<br />
+
-
**[[3kdy]] – SgTAM (mutant) + peptide derived chromophore <br />
+
-
**[[3kdz]] – SgTAM (mutant) + peptide derived chromophore + tyrosine<br />
+
-
**[[2rjr]], [[2rjs]] – SgTAM + peptide derived chromophore + substrate mimic<br />
+
-
**[[2qve]] – SgTAM + peptide derived chromophore + substrate mimic inhibitor<br />
+
-
 
+
-
*Ornithine-4,5-aminomutase complexes
+
-
 
+
-
**[[3koy]], [[3koz]] – CsORAS + CsORAE + cobalamine + deoxyadenosine + ornithine derivative – ''Clostridium stricklandii''<br />
+
-
**[[3kp0]], [[3kox]] – CsORAS + CsORAE + cobalamine + deoxyadenosine + 2,4-diaminobutyrate<br />
+
-
**[[3kow]], [[3kp1]] – CsORAS + CsORAE + cobalamine + deoxyadenosine + PLP<br />
+
-
 
+
-
*Lysine-2,3-aminomutase complexes
+
-
 
+
-
**[[2a5h]] – LAM + SAM + Zn + FeS4 + PLP + lysine – ''Clostridium subterminale''<br />
+
-
 
+
-
*D-lysine-5,6-aminomutase complexes
+
-
 
+
-
**[[1xrs]] – CsDLAM + cobalamine + deoxyadenosine + PLP <br />
+
-
 
+
-
*Glutamate-1-semialdehyde 2,1-aminomutase
+
-
 
+
-
**[[2hoy]] – SeGSAM – ''Synechococcus elongatus''<br />
+
-
**[[4e77]] – GSAM – ''Yersinia pestis''<br />
+
-
 
+
-
*Glutamate-1-semialdehyde 2,1-aminomutase complexes
+
-
**[[2zsl]], [[2zsm]], [[2epj]] – GSAM + PLP derivative – ''Aeropyrum pernix''<br />
 
-
**[[2hp1]], [[4gsa]] – SeGSAM + PLP <br />
 
-
**[[2hp2]] – SeGSAM + PLP + aminopentanoic acid derivative<br />
 
-
**[[2cfb]], [[2hoz]], [[3fq7]], [[3usf]] – SeGSAM + PLP derivative <br />
 
-
**[[3fq8]] – SeGSAM (mutant) + PLP derivative <br />
 
-
**[[2gsa]] – SeGSAM + PLP derivative + PLP<br />
 
-
**[[3gsb]], [[3fqa]] – SeGSAM + PLP derivative + gabaculine<br />
 
-
**[[2e7u]] – GSAM + PLP derivative – ''Thermus thermophilus''<br />
 
-
**[[3bs8]] – GSAM (mutant) + PLP derivative – ''Bacillus subtilis''<br />
 
-
**[[3l44]] – BaGSAM + PLP derivative – ''Bacillus anthracis''<br />
 
-
**[[3k28]] – BaGSAM + PLP <br />
 
-
**[[5hdm]] – GSAM + PLP + PMP - ''Arabidopsis thaliana'' <br />
 
-
**[[3k28]] – BaGSAM + PLP <br />
 
-
**[[5i92]] – GSAM + leucine - ''Pseudomonas aeruginosa'' <br />
 
-
}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Tyrosine aminomutase complex with peptide-derived chromophore cofactor (PDB code 2ohy)

Drag the structure with the mouse to rotate


References

  1. ↑ 1.0 1.1 Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway. Biochemistry. 2007 Jun 19;46(24):7205-14. Epub 2007 May 22. PMID:17516659 doi:10.1021/bi7003685

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Aminomutase"
Personal tools