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2hw2

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[[Image:2hw2.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin==
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|PDB= 2hw2 |SIZE=350|CAPTION= <scene name='initialview01'>2hw2</scene>, resolution 1.45&Aring;
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<StructureSection load='2hw2' size='340' side='right'caption='[[2hw2]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=RFP:RIFAMPICIN'>RFP</scene>
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<table><tr><td colspan='2'>[[2hw2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HW2 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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|GENE= arr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 Mycobacterium smegmatis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=RFP:RIFAMPICIN'>RFP</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw2 OCA], [https://pdbe.org/2hw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2hw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hw2 ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw2 OCA], [http://www.ebi.ac.uk/pdbsum/2hw2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hw2 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/A0QRS5_MYCS2 A0QRS5_MYCS2]
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== Evolutionary Conservation ==
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'''Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/2hw2_consurf.spt"</scriptWhenChecked>
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2HW2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW2 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Mycobacterium smegmatis]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: NAD(+) ADP-ribosyltransferase]]
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</jmolCheckbox>
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[[Category: Single protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hw2 ConSurf].
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[[Category: Baysarowich, J.]]
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<div style="clear:both"></div>
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[[Category: Junop, M.]]
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__TOC__
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[[Category: Wright, G.]]
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</StructureSection>
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[[Category: adp-ribosylation]]
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[[Category: Large Structures]]
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[[Category: protein-antibiotic complex]]
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[[Category: Mycolicibacterium smegmatis]]
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[[Category: rifampin]]
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[[Category: Baysarowich J]]
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[[Category: transferase]]
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[[Category: Junop M]]
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[[Category: Wright GD]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:36:14 2008''
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Current revision

Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin

PDB ID 2hw2

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