292d
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==INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX== | ==INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX== | ||
- | <StructureSection load='292d' size='340' side='right' caption='[[292d]], [[Resolution|resolution]] 1.00Å' scene=''> | + | <StructureSection load='292d' size='340' side='right'caption='[[292d]], [[Resolution|resolution]] 1.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[292d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[292d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=292D FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1Å</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=292d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=292d OCA], [https://pdbe.org/292d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=292d RCSB], [https://www.ebi.ac.uk/pdbsum/292d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=292d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
- | <div style="background-color:#fffaf0;"> | ||
- | == Publication Abstract from PubMed == | ||
- | The DNA fragment d(CG)3 was co-crystallized with N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized polyamine. The complex crystal contained one polyamine, 3 magnesium cations and one sodium cation per duplex of d(CG)3, and well diffracted the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a left-handed Z-DNA conformation, and the PA(24) molecule electrostatically interacted with the phosphate groups of the d(CG)3 duplex. | ||
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- | Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex.,Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:2060642<ref>PMID:2060642</ref> | ||
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- | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
- | </div> | ||
- | <div class="pdbe-citations 292d" style="background-color:#fffaf0;"></div> | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Hakoshima | + | [[Category: Hakoshima T]] |
- | [[Category: Kunisawa | + | [[Category: Kunisawa S]] |
- | + | [[Category: Ohishi H]] | |
- | [[Category: Ohishi | + | [[Category: Rich A]] |
- | [[Category: Rich | + | [[Category: Tomita K]] |
- | [[Category: Tomita | + | [[Category: Van Boom JH]] |
- | [[Category: | + | [[Category: Van Der Marel G]] |
- | [[Category: | + | [[Category: Wang AH-J]] |
- | [[Category: | + | |
- | + | ||
- | + |
Current revision
INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX
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Categories: Large Structures | Hakoshima T | Kunisawa S | Ohishi H | Rich A | Tomita K | Van Boom JH | Van Der Marel G | Wang AH-J