5ztb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:29, 27 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5ztb is ON HOLD
+
==Structure of Sulfurtransferase==
-
 
+
<StructureSection load='5ztb' size='340' side='right'caption='[[5ztb]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
Authors: Tanaka, Y., Chen, M., Narai, S., Yao, M.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5ztb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZTB FirstGlance]. <br>
-
Description: Structure of Sulfurtransferase
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
[[Category: Chen, M]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ztb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ztb OCA], [https://pdbe.org/5ztb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ztb RCSB], [https://www.ebi.ac.uk/pdbsum/5ztb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ztb ProSAT]</span></td></tr>
-
[[Category: Yao, M]]
+
</table>
-
[[Category: Tanaka, Y]]
+
== Function ==
-
[[Category: Narai, S]]
+
[https://www.uniprot.org/uniprot/TTUB_THET2 TTUB_THET2] Required for the 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2-thiouridine (m(5)s(2)U or s(2)T) (PubMed:16547008, PubMed:28439027). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is essential for cell growth at high temperatures (PubMed:16547008). Thiocarboxylated TtuB functions as the sulfur donor in the sulfurtransferase reaction catalyzed by TtuA (PubMed:28439027, PubMed:19037260). TtuB also functions as a protein modifier covalently attached to lysine residues of the target proteins TtuA and TtuC (PubMed:22467871). TtuB conjugation might play a regulatory role to ensure appropriate sulfur transfer in cells (PubMed:22467871).<ref>PMID:16547008</ref> <ref>PMID:19037260</ref> <ref>PMID:22467871</ref> <ref>PMID:28439027</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Thermus thermophilus HB27]]
 +
[[Category: Chen M]]
 +
[[Category: Narai S]]
 +
[[Category: Tanaka Y]]
 +
[[Category: Yao M]]

Current revision

Structure of Sulfurtransferase

PDB ID 5ztb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ztb"
Personal tools