2i3y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:05, 30 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2i3y.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of human glutathione peroxidase 5==
-
|PDB= 2i3y |SIZE=350|CAPTION= <scene name='initialview01'>2i3y</scene>, resolution 2.00&Aring;
+
<StructureSection load='2i3y' size='340' side='right'caption='[[2i3y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
+
<table><tr><td colspan='2'>[[2i3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I3Y FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
|GENE= GPX5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i3y OCA], [https://pdbe.org/2i3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i3y RCSB], [https://www.ebi.ac.uk/pdbsum/2i3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i3y ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i3y OCA], [http://www.ebi.ac.uk/pdbsum/2i3y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2i3y RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/GPX5_HUMAN GPX5_HUMAN] Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/2i3y_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i3y ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of human glutathione peroxidase 5'''
+
==See Also==
-
 
+
*[[Glutathione peroxidase|Glutathione peroxidase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2I3Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I3Y OCA].
+
-
[[Category: Glutathione peroxidase]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Bunkoczi, G.]]
+
[[Category: Bunkoczi G]]
-
[[Category: Delft, F Von.]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A.]]
+
[[Category: Gileadi O]]
-
[[Category: Gileadi, O.]]
+
[[Category: Johansson C]]
-
[[Category: Johansson, C.]]
+
[[Category: Kavanagh KL]]
-
[[Category: Kavanagh, K L.]]
+
[[Category: Oppermann U]]
-
[[Category: Oppermann, U.]]
+
[[Category: Rojkova A]]
-
[[Category: Rojkova, A.]]
+
[[Category: Sundstrom M]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Umeano C]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Weigelt J]]
-
[[Category: Umeano, C.]]
+
[[Category: Von Delft F]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: epididymal androgen related protein]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomic]]
+
-
[[Category: structural genomics consortium]]
+
-
[[Category: thioredoxin fold]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:39:18 2008''
+

Current revision

Crystal structure of human glutathione peroxidase 5

PDB ID 2i3y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2i3y"
Personal tools