2bf0

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==crystal structure of the rpr of pcf11==
==crystal structure of the rpr of pcf11==
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<StructureSection load='2bf0' size='340' side='right' caption='[[2bf0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='2bf0' size='340' side='right'caption='[[2bf0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BF0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bf0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BF0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sz9|1sz9]], [[1sza|1sza]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bf0 OCA], [https://pdbe.org/2bf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2bf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bf0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bf0 OCA], [http://pdbe.org/2bf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2bf0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bf0 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PCF11_YEAST PCF11_YEAST] Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Independently involved in RNA polymerase II transcript termination. Binds RNA. Seems to bridge RNA polymerase II and the native transcript and may be involved in dismantling the RNA polymerase II elongation complex.<ref>PMID:11344258</ref> <ref>PMID:15998810</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/2bf0_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/2bf0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Adeniran, V E]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Hollingworth, D]]
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[[Category: Adeniran VE]]
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[[Category: Kelly, G]]
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[[Category: Hollingworth D]]
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[[Category: Martin, S R]]
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[[Category: Kelly G]]
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[[Category: Noble, C G]]
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[[Category: Martin SR]]
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[[Category: Ramos, A]]
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[[Category: Noble CG]]
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[[Category: Smerdon, S J]]
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[[Category: Ramos A]]
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[[Category: Taylor, I A]]
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[[Category: Smerdon SJ]]
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[[Category: Phosphorylation]]
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[[Category: Taylor IA]]
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[[Category: Rna]]
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[[Category: Transcription]]
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Current revision

crystal structure of the rpr of pcf11

PDB ID 2bf0

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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