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5zx5

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m (Protected "5zx5" [edit=sysop:move=sysop])
Current revision (10:29, 27 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5zx5 is ON HOLD
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==3.3 angstrom structure of mouse TRPM7 with EDTA==
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<SX load='5zx5' size='340' side='right' viewer='molstar' caption='[[5zx5]], [[Resolution|resolution]] 3.28&Aring;' scene=''>
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Authors: Zhang, J., Li, Z., Duan, J., Li, J., Hulse, R.E., Santa-Cruz, A., Abiria, S.A., Krapivinsky, G., Clapham, D.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zx5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZX5 FirstGlance]. <br>
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Description: 3.3 angstrom structure of mouse TRPM7 with EDTA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.28&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
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[[Category: Clapham, D.E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx5 OCA], [https://pdbe.org/5zx5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zx5 RCSB], [https://www.ebi.ac.uk/pdbsum/5zx5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx5 ProSAT]</span></td></tr>
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[[Category: Abiria, S.A]]
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</table>
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[[Category: Li, J]]
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== Function ==
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[[Category: Santa-Cruz, A]]
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[https://www.uniprot.org/uniprot/TRPM7_MOUSE TRPM7_MOUSE] Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).<ref>PMID:11385574</ref>
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[[Category: Duan, J]]
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== References ==
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[[Category: Li, Z]]
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<references/>
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[[Category: Krapivinsky, G]]
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__TOC__
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[[Category: Zhang, J]]
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</SX>
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[[Category: Hulse, R.E]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Abiria SA]]
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[[Category: Clapham DE]]
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[[Category: Duan J]]
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[[Category: Hulse RE]]
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[[Category: Krapivinsky G]]
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[[Category: Li J]]
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[[Category: Li Z]]
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[[Category: Santa-Cruz A]]
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[[Category: Zhang J]]

Current revision

3.3 angstrom structure of mouse TRPM7 with EDTA

5zx5, resolution 3.28Å

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OCA

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