2iik

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[[Image:2iik.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)==
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|PDB= 2iik |SIZE=350|CAPTION= <scene name='initialview01'>2iik</scene>, resolution 2.55&Aring;
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<StructureSection load='2iik' size='340' side='right'caption='[[2iik]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2iik]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIK FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acyltransferase Acetyl-CoA C-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.16 2.3.1.16] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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|GENE= ACAA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iik OCA], [https://pdbe.org/2iik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iik RCSB], [https://www.ebi.ac.uk/pdbsum/2iik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iik ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iik OCA], [http://www.ebi.ac.uk/pdbsum/2iik PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iik RCSB]</span>
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[https://www.uniprot.org/uniprot/THIK_HUMAN THIK_HUMAN]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iik_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iik ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)'''
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==See Also==
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*[[Thiolase 3D structures|Thiolase 3D structures]]
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__TOC__
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==Disease==
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</StructureSection>
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Known disease associated with this structure: Pseudo-Zellweger syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=604054 604054]]
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==About this Structure==
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2IIK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIK OCA].
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[[Category: Acetyl-CoA C-acyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von.]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O.]]
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[[Category: Gorrec F]]
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[[Category: Gorrec, F.]]
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[[Category: Johansson C]]
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[[Category: Johansson, C.]]
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[[Category: Kavanagh K]]
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[[Category: Kavanagh, K.]]
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[[Category: Oppermann U]]
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[[Category: Oppermann, U.]]
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[[Category: Papagrigoriou E]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W.]]
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[[Category: Smee C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Sundstrom M]]
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[[Category: Smee, C.]]
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[[Category: Umeano C]]
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[[Category: Sundstrom, M.]]
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[[Category: Weigelt J]]
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[[Category: Umeano, C.]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J.]]
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[[Category: fatty acid metabolism]]
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[[Category: sgc]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:44:52 2008''
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Current revision

Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)

PDB ID 2iik

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