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2iir

From Proteopedia

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[[Image:2iir.jpg|left|200px]]
 
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{{Structure
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==Acetate kinase from a hypothermophile Thermotoga maritima==
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|PDB= 2iir |SIZE=350|CAPTION= <scene name='initialview01'>2iir</scene>, resolution 3.300&Aring;
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<StructureSection load='2iir' size='340' side='right'caption='[[2iir]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2iir]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIR FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetate_kinase Acetate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.1 2.7.2.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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|GENE= ack ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iir OCA], [https://pdbe.org/2iir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iir RCSB], [https://www.ebi.ac.uk/pdbsum/2iir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iir ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[1g99|1G99]], [[1tuu|1TUU]], [[1tuy|1TUY]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iir OCA], [http://www.ebi.ac.uk/pdbsum/2iir PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iir RCSB]</span>
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[https://www.uniprot.org/uniprot/ACKA_THEMA ACKA_THEMA] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%).<ref>PMID:10074080</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Acetate kinase from a hypothermophile Thermotoga maritima'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iir_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2IIR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIR OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Acetate kinase]]
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</jmolCheckbox>
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[[Category: Single protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iir ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Hasson, M S.]]
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[[Category: Hasson MS]]
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[[Category: Mukhopadhyay, S.]]
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[[Category: Mukhopadhyay S]]
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[[Category: Sanders, D A.]]
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[[Category: Sanders DA]]
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[[Category: acetate kinase]]
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[[Category: thermotoga maritima]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:44:58 2008''
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Current revision

Acetate kinase from a hypothermophile Thermotoga maritima

PDB ID 2iir

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