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2cby
From Proteopedia
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==Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis== | ==Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis== | ||
| - | <StructureSection load='2cby' size='340' side='right' caption='[[2cby]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='2cby' size='340' side='right'caption='[[2cby]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2cby]] is a 7 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2cby]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CBY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cby OCA], [https://pdbe.org/2cby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cby RCSB], [https://www.ebi.ac.uk/pdbsum/2cby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cby ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CLPP1_MYCTU CLPP1_MYCTU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Clp | + | *[[Clp protease 3D structures|Clp protease 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Alzari | + | [[Category: Alzari PM]] |
| - | [[Category: Mate | + | [[Category: Mate MJ]] |
| - | [[Category: Ortiz-Lombardia | + | [[Category: Ortiz-Lombardia M]] |
| - | [[Category: Portnoi | + | [[Category: Portnoi D]] |
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Current revision
Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis
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