2c5q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:35, 9 October 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of yeast YER010Cp==
==Crystal structure of yeast YER010Cp==
-
<StructureSection load='2c5q' size='340' side='right' caption='[[2c5q]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+
<StructureSection load='2c5q' size='340' side='right'caption='[[2c5q]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2c5q]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5Q FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2c5q]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C5Q FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5q OCA], [http://pdbe.org/2c5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5q RCSB], [http://www.ebi.ac.uk/pdbsum/2c5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5q ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5q OCA], [https://pdbe.org/2c5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c5q RCSB], [https://www.ebi.ac.uk/pdbsum/2c5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RRAAH_YEAST RRAAH_YEAST]] Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.<ref>PMID:24359411</ref>
+
[https://www.uniprot.org/uniprot/RRAAH_YEAST RRAAH_YEAST] Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.<ref>PMID:24359411</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 15: Line 15:
<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/2c5q_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/2c5q_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
Line 33: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 18824]]
+
[[Category: Large Structures]]
-
[[Category: Blondeau, K]]
+
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Graille, M]]
+
[[Category: Blondeau K]]
-
[[Category: Janin, J]]
+
[[Category: Graille M]]
-
[[Category: Leulliot, N]]
+
[[Category: Janin J]]
-
[[Category: Quevillon-Cheruel, S]]
+
[[Category: Leulliot N]]
-
[[Category: Schiltz, M]]
+
[[Category: Quevillon-Cheruel S]]
-
[[Category: Tilbeurgh, H van]]
+
[[Category: Schiltz M]]
-
[[Category: Pseudo-knot]]
+
[[Category: Van Tilbeurgh H]]
-
[[Category: Rraa]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Unknown function]]
+

Current revision

Crystal structure of yeast YER010Cp

PDB ID 2c5q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2c5q"
Personal tools