2coc
From Proteopedia
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==Solution structure of the C-terminal PH domain of FYVE, RhoGEF and PH domain containing protein 3 (FGD3) from human== | ==Solution structure of the C-terminal PH domain of FYVE, RhoGEF and PH domain containing protein 3 (FGD3) from human== | ||
| - | <StructureSection load='2coc' size='340' side='right' caption='[[2coc | + | <StructureSection load='2coc' size='340' side='right'caption='[[2coc]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2coc]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2coc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COC FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2coc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2coc OCA], [https://pdbe.org/2coc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2coc RCSB], [https://www.ebi.ac.uk/pdbsum/2coc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2coc ProSAT], [https://www.topsan.org/Proteins/RSGI/2coc TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FGD3_HUMAN FGD3_HUMAN] Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Inoue | + | [[Category: Large Structures]] |
| - | [[Category: Kigawa | + | [[Category: Inoue M]] |
| - | [[Category: Koshiba | + | [[Category: Kigawa T]] |
| - | [[Category: Li | + | [[Category: Koshiba S]] |
| - | [[Category: Muto | + | [[Category: Li H]] |
| - | + | [[Category: Muto Y]] | |
| - | [[Category: Tochio | + | [[Category: Tochio N]] |
| - | [[Category: Tomizawa | + | [[Category: Tomizawa T]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution structure of the C-terminal PH domain of FYVE, RhoGEF and PH domain containing protein 3 (FGD3) from human
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Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Koshiba S | Li H | Muto Y | Tochio N | Tomizawa T | Yokoyama S
