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2cgj
From Proteopedia
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==Crystal Structure of L-rhamnulose kinase from Escherichia coli in complex with L-fructose and ADP.== | ==Crystal Structure of L-rhamnulose kinase from Escherichia coli in complex with L-fructose and ADP.== | ||
| - | <StructureSection load='2cgj' size='340' side='right' caption='[[2cgj]], [[Resolution|resolution]] 2.26Å' scene=''> | + | <StructureSection load='2cgj' size='340' side='right'caption='[[2cgj]], [[Resolution|resolution]] 2.26Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2cgj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2cgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CGJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=LFR:BETA-L-FRUCTO-FURANOSE'>LFR</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cgj OCA], [https://pdbe.org/2cgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cgj RCSB], [https://www.ebi.ac.uk/pdbsum/2cgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cgj ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RHAB_ECOLI RHAB_ECOLI] Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). It could also play a role in the metabolism of some rare sugars such as L-fructose. Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Uridine triphosphate (UTP), cytidine 5-triphosphate (CTP), guanosine 5-triphosphate (GTP), and thymidine triphosphate (TTP) also can act as phosphoryl donors. It can also phosphorylate L-fuculose and L-xylulose.[HAMAP-Rule:MF_01535]<ref>PMID:14264882</ref> <ref>PMID:16674975</ref> <ref>PMID:5341476</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Grueninger D]] | |
| - | [[Category: Grueninger | + | [[Category: Schulz GE]] |
| - | [[Category: Schulz | + | |
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Current revision
Crystal Structure of L-rhamnulose kinase from Escherichia coli in complex with L-fructose and ADP.
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