2cq3

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==solution structure of RNA binding domain in RNA binding motif protein 9==
==solution structure of RNA binding domain in RNA binding motif protein 9==
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<StructureSection load='2cq3' size='340' side='right' caption='[[2cq3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2cq3' size='340' side='right'caption='[[2cq3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CQ3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cq3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQ3 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cq3 OCA], [http://pdbe.org/2cq3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2cq3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cq3 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cq3 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cq3 OCA], [https://pdbe.org/2cq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2cq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cq3 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cq3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RFOX2_HUMAN RFOX2_HUMAN]] RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.<ref>PMID:11875103</ref>
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[https://www.uniprot.org/uniprot/RFOX2_HUMAN RFOX2_HUMAN] RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.<ref>PMID:11875103</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Inoue, M]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Muto, Y]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Tsuda, K]]
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[[Category: Tsuda K]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rna binding protein]]
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[[Category: Rrm domain]]
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[[Category: Rsgi]]
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Current revision

solution structure of RNA binding domain in RNA binding motif protein 9

PDB ID 2cq3

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