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2crg

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==Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein==
==Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein==
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<StructureSection load='2crg' size='340' side='right' caption='[[2crg]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2crg' size='340' side='right'caption='[[2crg]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2crg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CRG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2crg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRG FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mta3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2crg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2crg OCA], [http://pdbe.org/2crg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2crg RCSB], [http://www.ebi.ac.uk/pdbsum/2crg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2crg ProSAT], [http://www.topsan.org/Proteins/RSGI/2crg TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2crg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2crg OCA], [https://pdbe.org/2crg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2crg RCSB], [https://www.ebi.ac.uk/pdbsum/2crg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2crg ProSAT], [https://www.topsan.org/Proteins/RSGI/2crg TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTA3_MOUSE MTA3_MOUSE]] Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (By similarity).
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[https://www.uniprot.org/uniprot/MTA3_MOUSE MTA3_MOUSE] Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Endo, H]]
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[[Category: Mus musculus]]
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[[Category: Hayashi, F]]
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[[Category: Endo H]]
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[[Category: Structural genomic]]
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[[Category: Hayashi F]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Yoshida, M]]
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[[Category: Yoshida M]]
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[[Category: Gene regulation]]
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[[Category: Helix turn helix]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transcription factor]]
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Current revision

Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein

PDB ID 2crg

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