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2cjb

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==Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine==
==Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine==
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<StructureSection load='2cjb' size='340' side='right' caption='[[2cjb]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='2cjb' size='340' side='right'caption='[[2cjb]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cjb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metbf Metbf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CJB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cjb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cim|2cim]], [[2cja|2cja]], [[2cj9|2cj9]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine--tRNA_ligase Serine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.11 6.1.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjb OCA], [https://pdbe.org/2cjb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cjb RCSB], [https://www.ebi.ac.uk/pdbsum/2cjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cjb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjb OCA], [http://pdbe.org/2cjb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cjb RCSB], [http://www.ebi.ac.uk/pdbsum/2cjb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cjb ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYS2_METBF SYS2_METBF] Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<ref>PMID:15364939</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Metbf]]
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[[Category: Large Structures]]
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[[Category: Serine--tRNA ligase]]
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[[Category: Methanosarcina barkeri str. Fusaro]]
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[[Category: Ahel, D]]
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[[Category: Ahel D]]
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[[Category: Ban, N]]
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[[Category: Ban N]]
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[[Category: Bilokapic, S]]
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[[Category: Bilokapic S]]
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[[Category: Gruic-Sovulj, I]]
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[[Category: Gruic-Sovulj I]]
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[[Category: Maier, T]]
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[[Category: Maier T]]
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[[Category: Soll, D]]
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[[Category: Soll D]]
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[[Category: Weygand-Durasevic, I]]
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[[Category: Weygand-Durasevic I]]
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[[Category: Ligase]]
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[[Category: Serine]]
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[[Category: Trna synthetase]]
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[[Category: Zinc ion]]
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Current revision

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine

PDB ID 2cjb

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