5qhq

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m (Protected "5qhq" [edit=sysop:move=sysop])
Current revision (08:54, 7 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5qhq is ON HOLD
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a==
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<StructureSection load='5qhq' size='340' side='right'caption='[[5qhq]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Talon, R., Krojer, T., Douangamath, A., Collins, P., Zhang, R., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Bullock, A.N.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qhq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHQ FirstGlance]. <br>
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Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of human FAM83B in complex with FMOPL000574a
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQP:1-[(4-fluorophenyl)methyl]benzimidazole'>GQP</scene></td></tr>
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[[Category: Zhang, R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhq OCA], [https://pdbe.org/5qhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhq RCSB], [https://www.ebi.ac.uk/pdbsum/5qhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhq ProSAT]</span></td></tr>
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[[Category: Collins, P]]
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</table>
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[[Category: Pinkas, D.M]]
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== Function ==
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[[Category: Fox, A.E]]
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[https://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>
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[[Category: Arrowsmith, C.H]]
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== References ==
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[[Category: Talon, R]]
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<references/>
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[[Category: Edwards, A]]
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__TOC__
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[[Category: Douangamath, A]]
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</StructureSection>
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[[Category: Krojer, T]]
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[[Category: Homo sapiens]]
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[[Category: Von Delft, F]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Bullock, A.N]]
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[[Category: Bountra C]]
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[[Category: Bufton, J.C]]
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[[Category: Bufton JC]]
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[[Category: Bullock AN]]
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[[Category: Collins P]]
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[[Category: Douangamath A]]
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[[Category: Edwards A]]
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[[Category: Fox AE]]
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[[Category: Krojer T]]
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[[Category: Pinkas DM]]
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[[Category: Talon R]]
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[[Category: Zhang R]]
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[[Category: Von Delft F]]

Current revision

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a

PDB ID 5qhq

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