5qic
From Proteopedia
(Difference between revisions)
												
			
			|  (New page: '''Unreleased structure'''  The entry 5qic is ON HOLD   Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrow...) | |||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z30620520== | |
| + | <StructureSection load='5qic' size='340' side='right'caption='[[5qic]], [[Resolution|resolution]] 1.34Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5qic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QIC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.34Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GX4:cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone'>GX4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qic OCA], [https://pdbe.org/5qic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qic RCSB], [https://www.ebi.ac.uk/pdbsum/5qic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qic ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | ||
| - | + | ==See Also== | |
| - | + | *[[Glycolate oxidase 3D structures|Glycolate oxidase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category:  | + | </StructureSection> | 
| - | [[Category:  | + | [[Category: Homo sapiens]] | 
| - | [[Category:  | + | [[Category: Large Structures]] | 
| - | [[Category:  | + | [[Category: Arrowsmith CH]] | 
| - | [[Category:  | + | [[Category: Bezerra GA]] | 
| - | [[Category:  | + | [[Category: Bountra C]] | 
| - | [[Category: Brennan | + | [[Category: Bradley AR]] | 
| - | [[Category:  | + | [[Category: Brandao-Neto J]] | 
| - | [[Category:  | + | [[Category: Brennan PE]] | 
| - | [[Category:  | + | [[Category: Douangamath A]] | 
| - | [[Category:  | + | [[Category: Edwards A]] | 
| - | [[Category:  | + | [[Category: Krojer T]] | 
| - | [[Category:  | + | [[Category: MacKinnon S]] | 
| - | [[Category:  | + | [[Category: Oppermann U]] | 
| - | [[Category:  | + | [[Category: Talon R]] | 
| + | [[Category: Yue WW]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z30620520
| 
 | |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bezerra GA | Bountra C | Bradley AR | Brandao-Neto J | Brennan PE | Douangamath A | Edwards A | Krojer T | MacKinnon S | Oppermann U | Talon R | Yue WW | Von Delft F
