6gko
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6gko is ON HOLD until Paper Publication Authors: Maj, P., Wilk, P., Jarmula, A., Weiss, M.S., Rode, W. Description: Mouse thymidylate synthase cocr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein== | |
| - | + | <StructureSection load='6gko' size='340' side='right'caption='[[6gko]], [[Resolution|resolution]] 1.84Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gko]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GKO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FGT:3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one'>FGT</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gko OCA], [http://pdbe.org/6gko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gko RCSB], [http://www.ebi.ac.uk/pdbsum/6gko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gko ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thymidylate synthase]] | ||
[[Category: Jarmula, A]] | [[Category: Jarmula, A]] | ||
[[Category: Maj, P]] | [[Category: Maj, P]] | ||
| - | [[Category: Weiss, M | + | [[Category: Rode, W]] |
| + | [[Category: Weiss, M S]] | ||
| + | [[Category: Wilk, P]] | ||
| + | [[Category: Fragment]] | ||
| + | [[Category: Fragment screening]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Transferase]] | ||
Current revision
Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein
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