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5ygv

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Current revision (08:29, 22 November 2023) (edit) (undo)
 
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==Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist==
==Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist==
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<StructureSection load='5ygv' size='340' side='right' caption='[[5ygv]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='5ygv' size='340' side='right'caption='[[5ygv]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ygv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YGV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ygv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YGV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8V6:(2Z,4E)-3-methyl-5-[(1S,4S)-2,6,6-trimethyl-4-[3-(4-methylphenyl)prop-2-ynoxy]-1-oxidanyl-cyclohex-2-en-1-yl]penta-2,4-dienoic+acid'>8V6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYR1, ABIP6, RCAR11, At4g17870, T6K21.50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8V6:(2Z,4E)-3-methyl-5-[(1S,4S)-2,6,6-trimethyl-4-[3-(4-methylphenyl)prop-2-ynoxy]-1-oxidanyl-cyclohex-2-en-1-yl]penta-2,4-dienoic+acid'>8V6</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ygv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ygv OCA], [http://pdbe.org/5ygv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ygv RCSB], [http://www.ebi.ac.uk/pdbsum/5ygv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ygv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ygv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ygv OCA], [https://pdbe.org/5ygv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ygv RCSB], [https://www.ebi.ac.uk/pdbsum/5ygv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ygv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref>
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[https://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ygv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ygv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Abscisic acid receptor 3D structures|Abscisic acid receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Akiyama, T]]
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[[Category: Large Structures]]
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[[Category: Iba, K]]
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[[Category: Akiyama T]]
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[[Category: Mimura, N]]
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[[Category: Iba K]]
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[[Category: Monda, K]]
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[[Category: Mimura N]]
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[[Category: Ohnishi, T]]
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[[Category: Monda K]]
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[[Category: Okamoto, M]]
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[[Category: Ohnishi T]]
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[[Category: Sue, M]]
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[[Category: Okamoto M]]
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[[Category: Takeuchi, J]]
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[[Category: Sue M]]
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[[Category: Todoroki, Y]]
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[[Category: Takeuchi J]]
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[[Category: Yajima, S]]
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[[Category: Todoroki Y]]
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[[Category: Hormone receptor]]
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[[Category: Yajima S]]

Current revision

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist

PDB ID 5ygv

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