2d6y

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==Crystal Structure of transcriptional factor SCO4008 from Streptomyces coelicolor A3(2)==
==Crystal Structure of transcriptional factor SCO4008 from Streptomyces coelicolor A3(2)==
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<StructureSection load='2d6y' size='340' side='right' caption='[[2d6y]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='2d6y' size='340' side='right'caption='[[2d6y]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2d6y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D6Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2d6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D6Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pb6|1pb6]], [[1z77|1z77]], [[2tct|2tct]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d6y OCA], [https://pdbe.org/2d6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d6y RCSB], [https://www.ebi.ac.uk/pdbsum/2d6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d6y ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO4008 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d6y OCA], [http://pdbe.org/2d6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d6y RCSB], [http://www.ebi.ac.uk/pdbsum/2d6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2d6y ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HTHR_STRCO HTHR_STRCO] Probably regulates the expression of its own gene and the adjacent SCO4007 gene by binding to two operator sites in the SCO4007-SCO4008 intergenic region.<ref>PMID:23831227</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/2d6y_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/2d6y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Strco]]
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[[Category: Large Structures]]
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[[Category: Hayashi, T]]
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[[Category: Hayashi T]]
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[[Category: Sakai, N]]
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[[Category: Sakai N]]
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[[Category: Tamura, T]]
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[[Category: Tamura T]]
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[[Category: Tanaka, I]]
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[[Category: Tanaka I]]
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[[Category: Tanaka, Y]]
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[[Category: Tanaka Y]]
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[[Category: Yao, M]]
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[[Category: Yao M]]
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[[Category: Gene regulation]]
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[[Category: Helix-turn-helix]]
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Current revision

Crystal Structure of transcriptional factor SCO4008 from Streptomyces coelicolor A3(2)

PDB ID 2d6y

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