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2dpk

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==The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger==
==The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger==
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<StructureSection load='2dpk' size='340' side='right' caption='[[2dpk]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2dpk' size='340' side='right'caption='[[2dpk]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dpk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dpk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpk OCA], [http://pdbe.org/2dpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dpk RCSB], [http://www.ebi.ac.uk/pdbsum/2dpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpk OCA], [https://pdbe.org/2dpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpk RCSB], [https://www.ebi.ac.uk/pdbsum/2dpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NAC1_CANFA NAC1_CANFA]] Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
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[[https://www.uniprot.org/uniprot/NAC1_CANFA NAC1_CANFA]] Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Canlf]]
[[Category: Canlf]]
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[[Category: Large Structures]]
[[Category: Abramson, J]]
[[Category: Abramson, J]]
[[Category: Sawaya, M]]
[[Category: Sawaya, M]]

Current revision

The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger

PDB ID 2dpk

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