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2dnx

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==Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA==
==Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA==
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<StructureSection load='2dnx' size='340' side='right' caption='[[2dnx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dnx' size='340' side='right'caption='[[2dnx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dnx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DNX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dnx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNX FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STX12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnx OCA], [http://pdbe.org/2dnx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dnx RCSB], [http://www.ebi.ac.uk/pdbsum/2dnx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnx ProSAT], [http://www.topsan.org/Proteins/RSGI/2dnx TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnx OCA], [https://pdbe.org/2dnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnx RCSB], [https://www.ebi.ac.uk/pdbsum/2dnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnx TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STX12_HUMAN STX12_HUMAN]] SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity).
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[https://www.uniprot.org/uniprot/STX12_HUMAN STX12_HUMAN] SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dnx ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dnx ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Syntaxin 3D structures|Syntaxin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Abe, T]]
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[[Category: Large Structures]]
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[[Category: Hirota, H]]
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[[Category: Abe T]]
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[[Category: Muto, Y]]
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[[Category: Hirota H]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Habc domain]]
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[[Category: Left-handed twist]]
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[[Category: Membrane fusion]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Snare]]
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[[Category: Syntaxin]]
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[[Category: Transport protein]]
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[[Category: Up and down three helix bundle]]
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[[Category: Vesicle transport]]
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Current revision

Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA

PDB ID 2dnx

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