5w27

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==Crystal structure of TnmS3 in complex with tiancimycin (TNM B)==
==Crystal structure of TnmS3 in complex with tiancimycin (TNM B)==
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<StructureSection load='5w27' size='340' side='right' caption='[[5w27]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='5w27' size='340' side='right'caption='[[5w27]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w27]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W27 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._CB03234 Streptomyces sp. CB03234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W27 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9VG:methyl+(2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate'>9VG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w29|5w29]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9VG:methyl+(2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate'>9VG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w27 OCA], [http://pdbe.org/5w27 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w27 RCSB], [http://www.ebi.ac.uk/pdbsum/5w27 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w27 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w27 OCA], [https://pdbe.org/5w27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w27 RCSB], [https://www.ebi.ac.uk/pdbsum/5w27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w27 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A125SA29_9ACTN A0A125SA29_9ACTN]
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==See Also==
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*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
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*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chang, C]]
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[[Category: Large Structures]]
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[[Category: Chang, C Y]]
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[[Category: Streptomyces sp. CB03234]]
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[[Category: Joachimiak, A]]
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[[Category: Chang C]]
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[[Category: Structural genomic]]
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[[Category: Chang CY]]
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[[Category: NatPro, Enzyme Discovery for Natural Product Biosynthesis]]
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[[Category: Joachimiak A]]
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[[Category: Nocek, B]]
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[[Category: Nocek B]]
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[[Category: Phillips, G N]]
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[[Category: Phillips Jr GN]]
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[[Category: Rudolf, J D]]
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[[Category: Rudolf JD]]
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[[Category: SHen, B]]
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[[Category: SHen B]]
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[[Category: Biosynthetic protein]]
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[[Category: Enzyme discovery for natural product biosynthesis]]
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[[Category: Glyoxalase/bleomycin resistance protein/dioxygenase superfamily]]
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[[Category: Lyase]]
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[[Category: Mcsg]]
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[[Category: Natpro]]
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[[Category: Psi-biology]]
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[[Category: Tiancimycin-binding protein]]
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Current revision

Crystal structure of TnmS3 in complex with tiancimycin (TNM B)

PDB ID 5w27

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