5qbx
From Proteopedia
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==Crystal structure of human Cathepsin-S with bound ligand== | ==Crystal structure of human Cathepsin-S with bound ligand== | ||
| - | <StructureSection load='5qbx' size='340' side='right' caption='[[5qbx]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='5qbx' size='340' side='right'caption='[[5qbx]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QBX FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B8V:(2S)-1-[4-(2-methoxyphenyl)piperidin-1-yl]-3-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propan-2-ol'>B8V</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B8V:(2S)-1-[4-(2-methoxyphenyl)piperidin-1-yl]-3-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propan-2-ol'>B8V</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qbx OCA], [https://pdbe.org/5qbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qbx RCSB], [https://www.ebi.ac.uk/pdbsum/5qbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qbx ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | ||
==See Also== | ==See Also== | ||
| - | *[[Cathepsin|Cathepsin]] | + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Ameriks MK]] | |
| - | [[Category: Ameriks | + | [[Category: Bembenek SD]] |
| - | [[Category: Bembenek | + | [[Category: Burley SK]] |
| - | [[Category: Burley | + | [[Category: Mirzadegan T]] |
| - | [[Category: Mirzadegan | + | [[Category: Shao C]] |
| - | [[Category: Shao | + | [[Category: Yang H]] |
| - | [[Category: Yang | + | |
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Current revision
Crystal structure of human Cathepsin-S with bound ligand
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Categories: Large Structures | Ameriks MK | Bembenek SD | Burley SK | Mirzadegan T | Shao C | Yang H
