2dyq

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==Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3==
==Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3==
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<StructureSection load='2dyq' size='340' side='right' caption='[[2dyq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<StructureSection load='2dyq' size='340' side='right'caption='[[2dyq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dyq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYQ FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBB3, FE65L2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyq OCA], [http://pdbe.org/2dyq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dyq RCSB], [http://www.ebi.ac.uk/pdbsum/2dyq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyq ProSAT], [http://www.topsan.org/Proteins/RSGI/2dyq TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyq OCA], [https://pdbe.org/2dyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyq RCSB], [https://www.ebi.ac.uk/pdbsum/2dyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyq ProSAT], [https://www.topsan.org/Proteins/RSGI/2dyq TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/APBB3_HUMAN APBB3_HUMAN]] May modulate the internalization of beta-amyloid precursor protein.
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[https://www.uniprot.org/uniprot/APBB3_HUMAN APBB3_HUMAN] May modulate the internalization of beta-amyloid precursor protein.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyq_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Kishishita, S]]
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[[Category: Large Structures]]
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[[Category: Nishino, A]]
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[[Category: Kishishita S]]
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[[Category: Structural genomic]]
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[[Category: Nishino A]]
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[[Category: Saijo, S]]
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[[Category: Saijo S]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Alzheimer's disease]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Protein binding]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3

PDB ID 2dyq

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