2edw
From Proteopedia
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==Solution structure of the I-set domain (3537-3630) of human obscurin== | ==Solution structure of the I-set domain (3537-3630) of human obscurin== | ||
- | <StructureSection load='2edw' size='340' side='right' caption='[[2edw | + | <StructureSection load='2edw' size='340' side='right'caption='[[2edw]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2edw]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2edw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EDW FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2edw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edw OCA], [https://pdbe.org/2edw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2edw RCSB], [https://www.ebi.ac.uk/pdbsum/2edw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2edw ProSAT], [https://www.topsan.org/Proteins/RSGI/2edw TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[Group:MUZIC:Obscurin|MUZIC:Obscurin]] | ||
*[[Obscurin|Obscurin]] | *[[Obscurin|Obscurin]] | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Hayashi F]] |
- | [[Category: Sano | + | [[Category: Sano R]] |
- | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
- | [[Category: Yoshida | + | [[Category: Yoshida M]] |
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[[Category: Z-disk]] | [[Category: Z-disk]] |
Current revision
Solution structure of the I-set domain (3537-3630) of human obscurin
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Categories: Homo sapiens | Large Structures | Hayashi F | Sano R | Yokoyama S | Yoshida M | Z-disk