5zyj

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'''Unreleased structure'''
 
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The entry 5zyj is ON HOLD until Paper Publication
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==Crystal structure of CERT START domain in complex with compound E16A==
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<StructureSection load='5zyj' size='340' side='right'caption='[[5zyj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zyj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZYJ FirstGlance]. <br>
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Description: Crystal structure of CERT START domain in complex with compound E16A
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[Category: Kobayashi, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyj OCA], [https://pdbe.org/5zyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zyj RCSB], [https://www.ebi.ac.uk/pdbsum/5zyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyj ProSAT]</span></td></tr>
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[[Category: Hanada, K]]
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</table>
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[[Category: Suzuki, M]]
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== Disease ==
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[[Category: Kumagai, K]]
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[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
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[[Category: Sakai, S]]
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== Function ==
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[[Category: Nakao, N]]
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[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
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[[Category: Egawa, D]]
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== References ==
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[[Category: Kawasaki, S]]
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<references/>
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[[Category: Hanzawa, H]]
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__TOC__
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[[Category: Ueno, M]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Egawa D]]
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[[Category: Hanada K]]
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[[Category: Hanzawa H]]
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[[Category: Kawasaki S]]
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[[Category: Kobayashi S]]
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[[Category: Kumagai K]]
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[[Category: Nakao N]]
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[[Category: Sakai S]]
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[[Category: Suzuki M]]
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[[Category: Ueno M]]

Current revision

Crystal structure of CERT START domain in complex with compound E16A

PDB ID 5zyj

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