6dn0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6dn0 is ON HOLD Authors: Langley, D.B., Roome, B., Christ, D. Description: Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.== | |
| + | <StructureSection load='6dn0' size='340' side='right'caption='[[6dn0]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6dn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4x4y 4x4y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DN0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dn0 OCA], [https://pdbe.org/6dn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dn0 RCSB], [https://www.ebi.ac.uk/pdbsum/6dn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dn0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Antibody 3D structures|Antibody 3D structures]] | |
| - | + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |
| - | [[Category: | + | *[[3D structures of human antibody|3D structures of human antibody]] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Christ D]] | ||
| + | [[Category: Langley DB]] | ||
| + | [[Category: Roome B]] | ||
Current revision
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
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