5w4c

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==Crystal structure of thioredoxin reductase from Cryptococcus neoformans in complex with FAD (FO conformation)==
==Crystal structure of thioredoxin reductase from Cryptococcus neoformans in complex with FAD (FO conformation)==
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<StructureSection load='5w4c' size='340' side='right' caption='[[5w4c]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='5w4c' size='340' side='right'caption='[[5w4c]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w4c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W4C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w4c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W4C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.255&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w4c OCA], [http://pdbe.org/5w4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w4c RCSB], [http://www.ebi.ac.uk/pdbsum/5w4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w4c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w4c OCA], [https://pdbe.org/5w4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w4c RCSB], [https://www.ebi.ac.uk/pdbsum/5w4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w4c ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/J9VRX9_CRYNH J9VRX9_CRYNH]
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==See Also==
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*[[Thioredoxin reductase 3D structures|Thioredoxin reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thioredoxin-disulfide reductase]]
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[[Category: Cryptococcus neoformans var. grubii H99]]
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[[Category: Barbosa, J A.R G]]
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[[Category: Large Structures]]
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[[Category: Bravo-Chaucanes, C P]]
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[[Category: Barbosa JARG]]
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[[Category: Felipe, M S.S]]
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[[Category: Bravo-Chaucanes CP]]
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[[Category: Valadares, N F]]
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[[Category: Felipe MSS]]
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[[Category: Oxidoreductase]]
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[[Category: Valadares NF]]
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[[Category: Thioredoxin reductase cryptococcus neoformans x-ray diffraction]]
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Current revision

Crystal structure of thioredoxin reductase from Cryptococcus neoformans in complex with FAD (FO conformation)

PDB ID 5w4c

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